For the treatment of early ejaculation, tadalafil and dapoxetine are two drugs that combine. When sexually stimulated, tadalafil improves blood flow to the penis and encourages erection in the penis after such stimulation. Dapoxetine, an SSRI (selective serotonin reuptake inhibitor), increases serotonin levels in nerves to enhance ejaculatory control and lengthen ejaculatory duration.